Tick borne diseases

Scanning electron micrograph of Ixodes scapularis (black-legged tick) by P. Catravas.
Research Overview:
I have been studying the ecology of tick-borne disease since the summer of 2000, Much of this work has been in collaboration with Richard S. Ostfeld and others. Projects include investigating the relationship between Lyme disease and the composition of the community of hosts for the Lyme vector, the black-legged tick (Ixodes scapularis) and  host relationships of another tick borne pathogen, Anaplasma phagocytophilum.  More recently, my students and I have studied how habitat restoration in the Albany Pine Bush Preserve impacts Lyme disease risk, how soil related characteristics affect the molting and survival of engorged black-legged ticks and whether stable isotope analysis can help us to determine the most important tick hosts.
Relevant Publications:
  • Hersh, M.H., R.S. Ostfeld, D.J. McHenry, M. Tibbetts, J.L. Brunner, M.E. Killilea, K. LoGiudice, K.A. Schmidt, F. Keesing. 2014. Co-Infection of Blacklegged Ticks with Babesia microti and Borrelia burgdorferi is Higher than Expected and Acquired from Small Mammal Hosts. PLOS ONE. 9:e99348. DOI: 10.1371/journal.pone.0099348.
  • Keesing, F., D. McHenry, M. Hersh, M. Tibbetts, J. Brunner, M. Killilea, K. LoGiudice, K. Schmidt, and R.S. Ostfeld. 2014. Prevalence of human-active and variant-1 strains of the tick-borne pathogen Anaplasma phagocytophilum in hosts and forests of eastern North America. American Journal of Tropical Medicine & Hygiene. 91:302-309. DOI: 10.4269/ajtmh.13-0525.
  • Keesing, F., M. Hersh, M. Tibbetts, D. McHenry, S. Duerr, J. Brunner, M. Killilea, K. LoGiudice, K. Schmidt, and R.S. Ostfeld. 2012. Reservoir competence of vertebrate hosts for Anaplasma phagocytophilum. Emerging Infectious Diseases. 18(12):213-216. DOI: http://dx.doi.org/10.3201/eid1812.120919.
  • Morlando, S.*, S. J. Schmidt, K. LoGiudice. 2012. Reduction in Lyme disease risk as an economic benefit of habitat restoration. Restoration Ecology. 20(4):498–504. doi: 10.1111/j.1526-100X.2011.00796.x
  • Keesing, F.A., J. Brunner, S. Duerr, M. Killilea, K. LoGiudice, K. Schmidt, H. Vuong, and R.S. Ostfeld. 2009. Hosts as ecological traps for the vector of Lyme disease. Proceedings of the Royal Society B. 276:3911-3919.
  • LoGiudice, K., S. Duerr, M. Newhouse, K. Schmidt, Killilea, M. and R.S. Ostfeld. Impact of host community composition on Lyme disease risk. Ecology 89(10), 2008, pp. 2841–2849.
  • LoGiudice, K., S. Duerr, M. Newhouse, K. Schmidt, Killilea, M. and R.S. Ostfeld. Impact of host community composition on Lyme disease risk. Ecology 89(10), 2008, pp. 2841–2849.
  • Catravas, P. and K. LoGiudice. (2008) SEM photograph of the black-legged tick (Ixodes scapularis). Bulletin of the Ecological Society of America 89:396. Bulletin tick
  • Brunner, J.L., K. LoGiudice, and R.S. Ostfeld. 2008. Estimating the importance of zoonotic reservoir hosts in pathogen transmission: prevalence and infectivity. Journal of Medical Entomology 45(1):139-147.
  • Ostfeld, R.S., and LoGiudice, K. 2003. Community disassembly, biodiversity loss, and the erosion of an ecosystem service. Ecology. 84:1421-1427.
  • LoGiudice, K., R.S. Ostfeld, K.A. Schmidt, and F. Keesing. 2003. The ecology of infectious disease: Effects of host diversity and community composition on Lyme disease risk. Proceedings of the National Academy of Sciences. 100:567-571.
  • Ostfeld, R.S., F. Keesing, and K. LoGiudice. 2006. Community ecology meets epidemiology: the case of Lyme Disease. Pages 28-40 In “Disease Ecology: community structure and pathogen dynamics”. S.K. Collinge and C. Ray (Editors). Oxford University Press.

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