Like I’ve mentioned in a few of my previous posts, this pandemic has brought on a lot of changes for everyone– but there is variation in how COVID-19 has impacted different groups of people. The experience of racial and ethnic minorities during this pandemic has been very different from other groups and is reflective of health outcomes that often exist for minorities in the U.S.
COVID-19
In New York City, the death rates for Black/African American individuals is much higher due to the virus, than it is for other racial/ethnic groups (1). The chart below shows the disproportionality of the effects of COVID on the population of African American individuals in a few states. 
Compared to the total state population, the majority of patients affected by COVID are African American (2).
These disparities exist not only during this pandemic, but in healthcare in general:
Reasons for the Disparity
People who belong to racial or ethnic minority groups experience the health care system differently than others– many of the existing disparities in society lead to poorer health outcomes, as well as greater vulnerability to viruses and other illnesses. Many minority groups live in heavily populated areas or live in households with multiple generations, where social distancing might not be possible (1). Many work hourly, so health benefits are not part of the package and health services become difficult to access (2). There is also a much higher population of racial and ethnic minorities in jails, prisons, etc. which are again, places that increase the risk of spread of viruses and other illnesses (1).
Also, because of the social distancing measures that have to be taken because of the pandemic, there has been a decrease in quality of care for patients who don’t speak English (4). Before, interpreters/translators could be present in person during a patient’s visit, which makes it much easier to translate and understand the patient’s concerns and symptoms. Now, a lot of interpreters have to work over the phone and it’s possible that a lot of information is getting lost in translation because it’s just harder to have a conversation and understand each other that way.
While the pandemic has affected everyone in one way or another, it has not affected everyone equally. The social determinants of health that I talked about in my first blog, in addition to factors such as racism, geographic location, and poverty, play a large part in deciding how an individual is affected. Unfortunately, the same level and quality of healthcare are not available to every person. Moving towards a system that addresses these disparities and provides excellent health care to each patient will involve first resolving the inequalities that exist in health care delivery in general and access to healthier food, exercise, etc. Additionally, training healthcare providers to better understand cultural differences and barriers to care could improve health outcomes for minority groups (3).
333,588 thoughts on “Impact of COVID on Racial & Ethnic Minorities”
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In Parkinson’s disease (PD), management of L-3,4-dihydroxyphenylalanine (l-DOPA)-related complications, such as l-DOPA induced dyskinesia and psychosis, remains inadequate, which poses a significant burden on the quality of life of patients. We have shown, in the hemi-parkinsonian rat model of PD, that the selective serotonin type 3 (5-HT3) receptor antagonists ondansetron and granisetron decreased the sev
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เลือกเล่นสล็อตได้แบบจุใจ ได้แปลงเป็นแบบอย่างการเดิมพันออนไลน์ยอดนิยมสูงที่สุดแบบหนึ่งในตอนไม่กี่ปีให้หลัง ด้วยการเข้าถึงที่ง่าย เกมที่นานาประการ รวมทั้ ับเพื่อการจ่ายรางวัลสูง สล็อตประสิทธิภาพ ก็เลยไม่น่าสนเท่ห์ใจที่ผู้เล่นหลายล้านคนทั้งโลกบันเทิงใจกับการหมุนวงล้อวันแล้ววันเล่า ในเนื้อหานี้ พวกเราจะเจาะลึกถึงแหล่งกำเนิดของสล็อตออนไลน์ คุยถึงโบนัสที่น่าส
CopelandByskov2785
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Results An extract-transform-load process was developed to extract relevant clinical and molecular data from their original sources and map them to OMOP. Further, the OMOP WebAPI was adapted to retrieve all data for a single patient and transfer them into the decision support Web application for enabling physicians to easily consult the prediction service including monitoring of transferred data. The evaluation of the appli
GalbraithOliver2075
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In conclusion, we identified a significant (52%) incidence of NOTCH1 mutations in CLL in the context of biclonal LPD, associated with an indolent clinical course.
Several lines of clinical research support the efficacy of Cognitive behavioral therapy (CBT) with a large number of population and various disease conditions, however, the true effects of CBT interventions on Quality of Life of br
HoveUlrich6450
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This pilot study has demonstrated the feasibility of safe percutaneous injection of C. acnes into sheep IVDs under fluoroscopic guidance. The design of follow-up sheep studies to investigate the potential of C. acnes to drive pathological changes within infected discs should now be pursued.The influence of a topically applied formulation containing components of natural moisturizing factor (NMF) on
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Participant experiences are highlighted to provide a better understanding of the job demands and job resources encountered. The framework of job demands and job resources gleaned from the study could be used for further research to manage and monitor motivational processes for academic staff, and to reduce strain due to high job demands.The focus on quantifiable data in sport performance has led to increm
AdairGalloway9619
Dac51 nmr
In this review, we discuss recent advances in the field of nanostructured drug delivery systems for orthopedic applications.A 54-year-old female patient was admitted to our outpatient clinic with back and low back pain. There were no remarkable physical or neurological findings in the two-year follow-up period of the patient. There were 39 lesions at 17 levels (mean diameter 5.93±2.77 [range, 1.00 to 12.2] mm) in entire ver
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acute hypoxemic respiratory failure.
Below a threshold of 15 cm H2O, ΔP was associated with significantly decreased morbidity in children with acute hypoxemic respiratory failure.
Pulse oximeters are used to measure [Formula see text] and pulse rate. These devices are either standalone machines or integrated into physiologic monitoring systems. Some smartphones now have pulse ox
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Practices of Provider-Initiated HIV Testing and Counseling (PITC) remains suboptimal in Côte d’Ivoire. The aim of this survey was to identify the practices and obstacles to PITC among healthcare professionals in Côte d’Ivoire. A nationally representative cross-sectional survey was conducted in 2018 by telephone among three separate samples of midwives, nurses and physicians practicing in Côte d’Ivoire. The number of HIV
FunchMartinsen7831
A-674563 mouse
Three ambient PM2.5 filters extracts were measured in the DTT assay, alongside mixtures of analytical standards prepared to match PAH concentrations in the filter extracts to test if the OP follows an additive model of toxicity. The additive prediction model did not accurately predict the DTT consumption in the assay for any of the prepared standard mixtures or ambient PM2.5 filter extracts, indicating a much more c
CollierHemmingsen6463
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Introduction Naturally occurring compounds play an essential role in the prevention and treatment of various cancers. There are more than 100 plant and animal based natural compoundscurrently in clinical use. Areas covered 1) The importance of natural products combinations in the prevention and treatment of cancer, 2) the need to maximize efficacy while minimizing side effects when using natural product combination
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In this review, we collect the reported harmful effects related to acquired metabolic disorders and diet in sperm parameters and male reproductive potential. Besides, we will discuss the novel findings regarding paternal epigenetic inheritance, particularly the ones induced by paternal diet rich in fats, obesity, and type 2 diabetes. We analyze the data attained with in vitro and animal models as well as in
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ODM208 ic50
Proximal MNBI was significantly lower in patients with both laryngopharyngeal and esophageal symptoms (17 cm above low esophageal sphincter [LES] L vs L + E vs E vs H = 3689.7 vs 2500.0 vs 3073.0 vs 3996.0; 15 cm above LES L vs L + E vs E vs H = 3155.9 vs 2553.4 vs 3198.9 vs 2985.2; P less then 0.001). Patients responded to proton pump inhibitor treatment also
HesselbergMelton3331
LDC203974
We aimed to determine the risk of postpartum infection and increased pain associated with use of condom-catheter uterine balloon tamponade (UBT) among women diagnosed with postpartum hemorrhage (PPH) in three low- and middle-income countries (LMICs). We also sought women’s opinions on their overall experience of PPH care.
This prospective cohort study compared women diagnose
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01) in serum and PEDV-specific secretory IgA (SIgA) in saliva (P less then 0.01) and nasal secretions (P less then 0.01). An increased number of intestinal CD3+ T cells, IgA-secreting cells and intraepithelial lymphocytes (P less then 0.05) were also observed. Furthermore, the protein expression levels of interleukin-6 and interferon-γ, relative to the control PEDV infection, were also significantly elevated
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Macrophages are a major component of the tumor microenvironment. M1 macrophages secrete pro-inflammatory factors that inhibit tumor growth and development, whereas tumor-associated macrophages
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The aim of the study was to compare the step kinematics, joint angles, and muscle activations between change of direction (COD) maneuvers with different angles and approach distances, suggested to require different strength and velocity demands. Twenty-three male soccer players completed eight COD tests consisting of both 4 and 20-m sprint approaches with one directional change which varied between each COD test (45, 90,
HwangMclaughlin9599
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OBJECTIVE This study aimed to examine the impact of trainee involvement in performing tympanoplasty or tympano-ossiculoplasty on outcomes. METHODS A retrospective analysis was performed of a prospective database of all patients undergoing tympanoplasty and tympano-ossiculoplasty in a single centre during a three-year period. Patients were divided into three primary surgeon groups consultants, fel
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The excitation and propagation of amplified spontaneous emission (ASE) along these active waveguides are experimentally demonstrated and numerically analyzed. The findings of this work offer possibilities for the realization of ultra-thin electrically driven colloidal laser devices, providing critical advantages including single-mode lasing and high electrical conduction.Heavy fuel oil ash (HFOA) is generated as a
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These findings demonstrate that phenyl isoxazole derivatives possess great potential for protective management in cornfields.Understanding charge transport through molecular wires is important for nanoscale electronics and biochemistry. Our goal is to establish a simple first-principles protocol for predicting the charge transport mechanism in such wires, in particular the crossover from coherent tunneling for s
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In today’s fast-paced society, finding harmony has become increasingly crucial. This is where mindfulness comes into action. Meditation, which has acquired attention across the globe, delivers a way to boost your mental and bodily well-being. In this article, we examine the advantages of engaging in mindfulness and how it supports a healthier lifestyle.
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AdMSCs-derived Evs overexpressing miR-15a repressed proliferation, migration, and invasion, while it promoted the apoptosis of CRC cells via downregulation of KDM4B. These in vivo findings were reproduced in vitro on CRC immune evasion. Collectively, adMSCs-derived Evs overexpressing miR-15a restricted the immune evasion of CRC via the KDM4B/HOXC4/PD-L1 axis.Purpose Congenital nystagmus (CN) is a genetically
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In summary, this tri-culture inflammation model mimics the microenvironment, the cellular crosstalk and the molecular events that take place during neuroinflammation. It provides a robust in vitro model for studying neuroinflammation mechanisms and screening for potential therapeutics to treat various neurodegenerative diseases.Complete loss of petals, or becoming apetalous, has occurred independently in many flow
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Based on sequence homology, substrate specificity, and subcellular localization, CLH, PPH, and CLD1 belong to different types of dephytylase, which prompted us to re-examine the dilemmas and missing links that still exist in Chl metabolism. This review thus focuses on the hitherto unanswered questions involving the Chl dephytylation reaction by highlighting relevant literature, updating recent progres
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The adrenal cortex is an endocrine organ comprised of three histological zones, the outermost zona glomerulosa, the intermediate zona fasciculata, and the innermost zona reticularis. High plasticity of the adrenal gland is supported by pools of stem and progenitor cells that are deployed to sustain physiological and homeostatic demands. In recent decades, exciting new discoveries elucidating the identity, function,
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Perovskite solar cells (PSCs) have triggered a research trend in solar energy devices in view of their high power conversion efficiency and ease of fabrication. However, more delicate strategies are still required to suppress carrier recombination at charge transfer interfaces, which is the necessary path to high-efficiency solar cells. Here, a p-p+ homojunction was constructed on basis of NiO film to enhance hole tra
HyllestedHolman7459
Almorexant clinical trial
No use of general anesthesia or sedation was needed in our experience. Corneal shields have been used. Results After only two sessions of the Q-switched laser performed 1 year apart, the result was excellent with a 95% of clinical response. No side effect was observed. Conclusions In our experience, Q-switched NdYAG laser is an effective treatment for NO with no necessity of high number of treatment
MeredithWalters3546
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Main outcome measures Primary outcome was the catheter dislocation rate in the first 48 h. Secondary outcomes were pain scores and sensory blockade. Results There was no statistically significant difference between the two techniques regarding dislocation of the catheters at 24 or 48 h (at 48 h, Group 1 15%, Group 2 2.6%, P = 0.109). Also pain scores, sensory blockade and rescue doses of ropivacai
HejlesenSamuelsen3489
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Amidst the coronavirus disease 2019 (COVID-19) pandemic, there is uncertainty regarding potential lasting impacts on children’s health and educational outcomes. Play, a fundamental part of childhood, may be integral to children’s health during crises. We undertook a rapid review of the impact of quarantine, isolation and other restrictive environments on play and whether play mitigates adverse effects
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The purpose of the study is to compare conventional linear and fingertip ultrasound transducers, for the evaluation of umbilical catheters, with radiography. Fingertip ultrasound transducers have the potential to simplify sonographic examination due to their small size and ability to fit on a finger.
A prospective, IRB approved comparative study was performed. Linear and finger
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difference was not statistically significant. In adjusted analyses, RR, biopsy recommendation rates, and PPV1 were improved for DBT versus DM (P ≤ .001). Compared with DM, a higher proportion of DBT-detected cancers were invasive (70% [238 of 340] vs 68.5% [37 of 54]) and had poor prognoses characteristics (32.6% [76 of 233] vs 25.0% [nine of 36]). Conclusion Favorable outcomes with digital breast tomosynthesis screening
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Quantitation of surface roughness is difficult, if subtle, but significant differences cause an uncommon variance. We used atomic force microscopy to measure the surface roughness of polyethylene terephthalate (PET) fibers before and after a 30 s plasma treatment of 300 W. Samples were measured multiple times at different locations, in four scan sizes. The surface roughness was expressed in terms of nine roughn
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In conclusion, our strategy of selectively ablating CXCR4 positive leukemic cells by administering the T22-DITOX-H6 nanoparticle could be a promising treatment, especially in patients undergoing AML relapse after chemotherapy, in which leukemic cells overexpress CXCR4.
Retrograde and anterograde transsynaptic viral vectors are useful tools for studying the input and output orga
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Here, we show that Atg36 phosphorylation is abolished in cells lacking Pex3 or expressing a Pex3 mutant defective in the interaction with Atg36, suggesting that the interaction with Pex3 is essential for the Hrr25-mediated phosphorylation of Atg36. Using recombinant proteins, we further demonstrated that Pex3 directly promotes Atg36 phosphorylation by Hrr25. A co-immunoprecipitation analysis revealed that the interaction of Atg36
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In both of the studied species, extensins were recorded in the transmitting tissues. Arabinogalactan proteins as well as weakly and highly esterified pectins and extensins occurred in close proximity to calcium oxalate crystals in both Taraxacum and Pilosella cells.Mass spectrometry methods are commonly used in the identification of peptides and biomarkers. Due to a relatively low abundance of proteins i
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Additional investigations revealed that chemotherapy resistance and malignant stemness were influenced by upregulating NANOG, OCT4, and SOX2, and the expression of these targets significantly attenuated by genetically and pharmacologically hindering the activities of YAP1 and STAT3 in vivo and in vitro Therapeutically, the dual inhibition of YAP1 and STAT3 elicits a long-lasting therapeutic response by lim
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While in some cases such interaction may lead to pathological consequences, in some other cases beneficial effects can be identified. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.For brain computer interfaces (BCI), the immune response to implanted electrodes is a major biological cause of device failure. Bioactive coatings such as neural adhesion molecule L1 have been shown to improve the bioc
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Optical nanoantennas can convert propagating light to local fields. The local-field responses can be engineered to exhibit nontrivial features in spatial, spectral and temporal domains, where local-field interferences play a key role. Here, we design nearly fully controllable local-field interferences in the nanogap of a nanoantenna, and experimentally demonstrate that in the nanogap, the spectral disp
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CYP2B7P, CYP2F2P and CYP4F26P were enriched in arachidonic acid metabolism pathway. The qRT-PCR analysis validated the lower expression of pseudogenes CYP2F2P and CYP2B7P in NPC tissues and cell lines compared to paracancerous tissues and normal human nasopharyngeal epithelial cell line. CYP2B7P overexpression weakened migratory and invasive capacity of NPC cell line. Moreover, the expression pattern of tho
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Nanocomposite hydrogels capable of undergoing manufacturing process have recently attracted attention in biomedical applications due to their desired mechanical properties and high functionality. 3D printing nanocomposite hydrogels of hyaluronic acid (HA)/nanodiamond (ND) revealed that the addition of ND with the low weight ratio of 0.02 wt% resulted in higher compressive force and gel breaking point, compar
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There is a growing interest in mediating information transfer between biology and electronics. By the addition of redox mediators to various samples and cells, one can both electronically obtain a redox “portrait” of a biological system and, conversely, program gene expression. Here, we have created a cell-based synthetic biology-electrochemical axis in which engineered cells process molecular cues, producing an output
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We detected minor Aedes habitat segregation; some periurban areas that were highly suitable for Ae. albopictus were unsuitable for Ae. aegypti. Fine-scale empirical models like those presented here have the potential for precise risk assessment and the improvement of operational applications to control container-breeding Aedes mosquitoes.Visceral leishmaniosis is one of the most fatal old-world neglected disease with
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Facing severe PM2.5 pollution, China has adopted a series of clean air policies since 2013, but PM2.5 concentrations in China remain serious. Weighing both sustainable development and environmental protection, the Environmental Protection Tax Law was implemented in 2018 in China. This research employed a Bayesian space-time model to identify the impacts of the environmental protection tax on PM2.5 pollution (IEPTPM
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Crystallography is an important science that impacts many areas of research. The number of users of crystallographic techniques has increased significantly over the past few decades, as diffractometers have become readily available and many commercial programs with user-friendly interfaces have been developed. The growth in computing power has led to the development of advanced methods that were unt
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Down syndrome (DS), caused by trisomy of chromosome 21, is the most significant risk factor for early-onset Alzheimer’s disease (AD); however, underlying mechanisms linking DS and AD remain unclear. Here, we show that triplication of homologous chromosome 21 genes aggravates neuroinflammation in combined murine DS-AD models. Overexpression of USP25, a deubiquitinating enzyme encoded by chromosome 21, results in
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